News

Press Releases

Gliknik Licensee Pfizer Receives Orphan Drug Designation From U.S. Food and Drug Administration for Drug Candidate Directed Towards Rare Neurological Disorder —Read More

Gliknik Expands Clinical Development Team with New Senior Director and Adds Board Members —Read More

Gliknik Enters Into Licensing Agreement With Pfizer For Drug Candidate Targeting Autoimmune Diseases —Read More

Gliknik adds Incyte President & Ceo Paul A. Friedman to its Board if Directors —Read More

Gliknik Announces Interim Clinical Data From Use of Its Immunomodulator Drug Candidate in Multiple Myeloma Patients —Read More

Gliknik Raises $4.9 Million in Series B Financing Led by Baxter Ventures —Read More

Published Preclinical Data Demonstrate Ability of Gliknik’s Recombinant StradomersTM to Mimic Anti-Autoimmune Effect of IVIG —Read More

National Cancer Institute Awards Gliknik Up to $1.5 Million in SBIR Funding —Read More

Publications

Fc fusion as a platform technology: potential for modulating immunogenicity —Download pdf
Ditza Levin, Basil Golding, Scott E. Strome, and Zuben E. Sauna CellPress – Trends in Biotechnology 2014 :1-8. Published January, 2015.

Combination Immunotherapy after ASCT for Multiple Myeloma Using MAGE-A3/Poly-ICLC Immunizations Followed by Adoptive Transfer of Vaccine-Primed and Costimulated Autologous T Cells —Download pdf
Aaron P. Rapoport, Nicole A. Aqui, Edward A. Stadtmauer, et al. Clin Cancer Res. 2014; 20:1355-1365. Published online first February 11, 2014.

Recombinant IgG2a Fc (M045) multimers effectively suppress experimental autoimmune myasthenia gravis —Download pdf
Muthusamy Thiruppathia, Jian Rong Shenga, Liangcheng Lia, Bellur S. Prabhakara, Matthew N. Meriggioli Journal of Autoimmunity. January 2014; 1-10.

Beneficial effect of a multimerized immunoglobulin Fc in an animal model of inflammatory neuropathy (experimental autoimmune neuritis) —Download pdf
Marzieh Niknami, Min-Xia Wang, Toan Nguyen, John D. Pollard Journal of the Peripheral Nervous System. 2013; 18:141–152.

Tumour antigen targeted monoclonal antibodies incorporating a novel multimerisation domain significantly enhance antibody dependent cellular cytotoxicity against colon cancer—Download pdf
Ajay Jain a,b,c, Bhawna Poonia d,j, Edward C. So a,b,j, Ravi Vyzasatya b, Erin E. Burch c, Henrik S. Olsen e, Emmanuel Y. Me´rigeon e, David S. Block e,Xiaoyu Zhang c, Dan H. Schulze c,f, Nader N. Hanna b, William S. Twadell g, Harris G. Yfantis g,h, Siaw L. Chan e, Ling Cai i, Scott E. Strome c European Journal of Cancer 2013; 49:3344-3352. Published July, 18 2013.

Induction of MAGE-A3 and HPV-16 immunity by Trojan vaccines in patients with head and neck carcinoma —Download pdf
Caroline J. Voskens, Duane Sewell, Scott E. Strome Head Neck. December 2012; 34(12): 1734-1746.

Fully recombinant IgG2a Fc multimers (stradomers) effectively treat collagen-induced arthritis and prevent idiopathic thrombocytopenic purpura in mice —Download pdf
Ajay Jain, Henrik S. Olsen, Ravi Vyzasatya, Erin Burch, Yukimi Sakoda, Emmanuel Y. Mérigeon, Ling Cai, Changwan Lu, Ming Tan, Koji Tamada, Dan Schulze, David S. Block, Scott E. Strome Arthritis Research & Therapy. 2012; 14:R192.